I can vouch for Jellyfin - Nothing harder than setting up docker and connecting via Finamp. Been a very “set it and forget it” experience for me.

I myself have separate /Disks folder where I mount all my internal disks on boot. Not sure how “standard” such setup is, but it helped me keep my NTFS and Linux disks tidy and out of my way. For what I know you can mount your drives anywhere you like

Human eye can’t see more than 1080p anyway, so what’s the point